Comparison of Dimensionality
Reduction Methods for Single Cell RNAseq Analysis
In this study, we compared 11 different Dimensionality reduction (DR) methods on 28 publicly available scRNAseq data sets that cover a range of sequencing techniques and sample sizes. The performance of different DR methods are evaluated in terms of their accuracy and robustness in both cell clustering and lineage reconstruction downstream analyses.
Data, Code, and Scripts
All data, analysis code and scripts used in the paper are available at github.
Shiquan Sun, Jiaqiang Zhu, Ying Ma and Xiang Zhou
(2019). Accuracy, Robustness and Scalability of Dimensionality
Reduction Methods for Single Cell RNAseq Analysis. bioRxiv. 641142.